thousands of illnesses afflicting human beings


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inches This drug has recently won acceptance for use in The european countries and the United States. Studies done show which the drug “targets the tumour to control in four areas: in the web page where hypersecretion starts, in GH release, IGF-1 in addition to the symptoms associated with the disease (Unknown, 2004). ” While the drug have been approved, you may still find contraindications to taking this such as a sufferer who has an irregular or slow heartrate, or blood sugar levels which are both too high or perhaps too low.


Although gigantism begins prior to puberty, the “majority of giants sooner or later demonstrate highlights of acromegaly, that the imply age to get the onset is within the next decade of life. Even a congenital onset of GH extra has been advised by thready growth acceleration occurring inside the first few weeks of life in young children with recorded gigantism (http://jcem.endojournals.org/cgi/content/full/84/12/4379).” Although there is not any accurate amount of people who have acquired gigantism, the illness is so exceptional that presently there have only been around 90 reported circumstances.

Prognosis and Complications

There is not any prevention intended for gigantism, nevertheless the patient can expect a good prognosis from pituitary surgery due to the ability to limit GH creation.

An individual may develop problems such as “the development of extra sexual characteristics may be late, and surgical treatment and the radiation can equally lead to zero other pituitary hormones creating hypothyroidism, well known adrenal insufficiency, hypogonagism, and in exceptional cases diabetes insipidus (www.shands.org/health/information/001174trt.htm).”

Gigantism generally “occurs since an separated disorder, nonetheless it may also be a feature of an actual medical condition such as multiple endocrine neoplasia (MEN) type-1, McCune-Albright syndrome (MAS), neurofibromatosis, Carney complex (http://jcem.endojournals.org/cgi/content/full/84/12/4379).”


Gigantism is a disease that affects an individual prior to growing up, unlike the similar disease acromegaly, which in turn strikes later on. The condition is caused by increased growth hormone secretion. This body hormone “stimulates the growth of our bones, muscles, and lots of internal organs and excessive sums lead to abnormally robust regarding all of these tissues. Certain unusual tumors with the pancreas and lungs could also produce human hormones that stimulate the pituitary to produce abnormal amounts of human growth hormone (http://www.merck.com/mmhe/sec13/ch162/ch162e.html).”

The condition can be treated in several ways including surgery, drug therapy and radiation. The prognosis will work for an individual who can be properly diagnosed and will get treatment.

While there is no methods to prevent gigantism, it is an really rare disease and is called an orphan disease just for this rarity.

Research workers are currently searching for a cure to the disease in addition to a number of studies underway to help them with their efforts. It is wished that researchers will one day find a way to halt this disease and the persons affected can lead usual lives with no disfiguration.


Acromegaly and Gigantism. (accessed 20 November, 2004). http://www.merck.com/mmhe/sec13/ch162/ch162e.html).

Gigantism. (accessed 20 Nov, 2004). http://jcem.endojournals.org/cgi/content/full/84/12/4379).

Gigantism. (accessed 20 The fall of, 2004). www.mayoclinic.com).

Gigantism. (accessed 20 Nov, 2004). www.shands.org/health/information/001174trt.htm).

Gigantism. (accessed 20 Nov, 2004). www.thedoctorslounge.net/clinlounge/diseases/endocrinology/gigantism).

Pituitary Gigantism. (accessed 20 November, 2004). www.medfamily.org/diagnosis/P/diagnosis-terms-Pituitary_gigantism).

Simmons, Kirt E. (01 October, 1999). “Growth Hormone and Craniofacial Alterations: Preliminary Info From Research in Turner’s Syndrome. inch Pediatrics.

Skatssoon, Judy. (21 May, 2002). “NSW: Fresh discovery can result in cure to get dwaftism, gigantism. ” AAP General Media (Australia).

Not known. (01 Summer, 2004). “Novartis Sandostatin BIG approved in Japan intended for Acromegaly. Around the world Biotech.

  • Category: science
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  • Project Type: Essay