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pharm ch5 sympathomiometic anticholinergic drugs

03/12/2020
719
Common Name: Albuteral

precisely what are the trade names?

Proventil, Ventolin, ProAir, etc

Type drug of Albuterol

Short performing beta agonist (SABA)

Indications pertaining to Albuterol

Rescue drug for bronchospasm, breathing difficulties, and COPD exacerbation, and maintenance medicine for bronchial asthma and COPD.

Delivery method of albuterol

SVN and pMDI

Standard dosage of albuterol

pMDI 2 puffs

SVN 2 . 5mg; 0. 5ml of 0. five per cent solution

Duration of albuterol

4-6 hours

Rate of recurrence of albuterol

QID? Queen 4 hours

start action of albuterol

5-15 min

Peak a result of albuterol

30-60 min

albuterol exists as?

thick syrup, tablets, prolonged release tablets

Why is Albuterol called a racemic

Albuterol is made up of R & S isomers

3rd there’s r isomer is definitely the potent isomer in albuterol and offers few unwanted effects.

S isomer is considered to be inert, but takes up space on radio site.

May cause bronchoconstriction

Universal name: Salmeterol xinafoate

What is the Trade Identity

Serevent

What type medication is (G. )Salmeterol Xinafoate/ (T. ) Serevent

LABA long performing beta agonist

Delivery Method of (G) Salmeterol Xinafoate/ (T) Serevent

Diskus DOTS PER INCH pMDI

Duration of (G) salmeterol Xinafoate/ (T) Serevent

12 hours (LABA)

Frequency of Salmeterol Xinafoate/ (T) serevent

PUT MONEY

Is usually Salmeterol Xinafoate/ (T) serevent a Recovery Drug?

why or perhaps why not

NO . Not for use during acute exacerbations. All LABA, 12+ hour increase risk for sudden death from breathing difficulties complications when ever used exclusively.

Generic Name Levalbuterol. What is transact name?

Xopenex

what kind drug is (G) Levalbuterol/ (T) Xopenex

SABA brief acting beta agonist

Indications to get (G) levalbuterol/ (T) Xopenex

Rescue drug for bronchospasm, asthma, and COPD exacerbation.

Maintenance drug pertaining to asthma and COPD

Delivery Way for (G) levalbuterol/ (T) Xopenex

SVN pMDI

Duration of (G) levalbuterol/ (T) xopenex

3-8 several hours

Regularity of (G) levalbuterol/ (T) xopenex

q 4-6 hr

What is special regarding levalbuterol when compared with albuterol?

Levalbuterol is the R isomer of albuterol, therefore it is more potent and has fewer side effects.

Generic identity: Formoterol, fumarate

Trade name?

Foradil, DPI perforomist SVN

What type medicine is Formoterol, Fumarate?

(T) foradil, DPI perforomist SVN

Long acting Beta agonist LABA

Indications for (G) Formoterol (T) foradil DOTS PER INCH Perforomist (SVN)

maintenance medication for breathing difficulties and COPD to PREVENT severe exacerbations

Prevent EIA ( workout induced asthma)

Delivery method of (G) formoterol (T) foradil DPI Perforomist (SVN)

Period?

aerolizer DPI, SVN

12 hr

T/F LABA could be a rescue medicine or maintenance

FALSE, repeated dosing triggers an accumulation effect that can be dangerous

Common name: Aformoterol tartrate

Trade Brand?

Brovana

(G) aformoterol tartrate (T) Brovana

type medicine?

Sign?

LABA very long acting beta agonist

maintenance medication for pts w/ COPD

(G) aformoterol tartrate (T) Brovana

Delivery method?

Duration?

SVN, 12 hours

T/F aformoterol is much less potent than Formoterol

False Aformoterol tartrate/ Brovana may be the R isomer of Formoterol which means it truly is more potent and has fewer side effects.

Generic Olodaterol

Trade Name?

Striverdi

(G) Olodaterol/ (T) Striverdi

type medication?

Indicator?

LABA, lengthy acting Beta Agonist

maintenance medication for pts w/ COPD

***not intended for pts w/ bronchial asthma @ on this occasion

(G) olodaterol/ (T) Striverdi

Delivery technique?

Length?

Respimat Inhaler/ SMI/ Slower mist inhaler

twenty four hrs

Generic ” Indacaterol Maleate

Precisely what is trade name?

Arcapta

(G) Indacaterol Maleate (T) Arcapta

Type medicine?

Indicator?

LABA long acting beta agonist

maintenance medicine for pts w/ COPD

**not intended use w/ pts w/ asthma at this time

(G) Indacaterol Maleate (T) Arcapta

Delivery Method?

Duration?

Neohaler DOTS PER INCH

all night

Exactly how are Bronchial easy muscles activated

Bronchial soft muscles will be stimulated simply by sympathetic hormones (Catecholamines) going around in the bloodstream

How do sympathomimetic (Beta-adrenergic) drugs function

sympathomi medications directly trigger bronchodilation simply by increasing cyclic AMP (cAMP) which cause bronchodilation (EX albuterol)

Just how can anticholinergic (Parasympatholytic) drugs work

otherwise known as muscarinic antagonist

block bronchoconstricting effeects of cyclic GMP (cGMP) compound produced by parasympathetic system that causes bronchoconstriction

when is racemic epinephrine (Vaponefrin, Micronefrin) used?

Commonly used to get alpha properities

topical vasoconstrictor to get treating air passage edema

croup & laryngeal edema (post-extubation stridor)

Generic Name:

Ipratropium Bromide

what is trade name

Atrovent

(G) Ipratropium Bromide/ (T) Atrovent

Type drug?

Indicator?

Anticholinergic, Brief acting muscarinic antagonist, SAMA

Repair TREATMENT of bronchospasm in COPD

(G) ipratropium bromide/ (T) atrovent

delivery method?

Duration?

SVN, pMDI-HFA

pMDI-HFA two puffs (17mcg/puff)

SVN, 0. your five mg in 2 . a few ml unit dose

4-6 hours

T/F atrovent and albuterol possess a synergistic relationship

Accurate

what is one contraindication for iproprium bromide/atrovent

Contraindicated with pts with hypersensitivity to soy lecithin

ask about almond or soy allergies before admin

(G)Tiotropium Bromide

Operate name

Spiriva

(G) tiotropium Bromide (T) Spiriva

type drug?

Indications

LAMA long operating muscarinic villain

Repair drug pertaining to COPD and asthma

(G) tiotropium Bromide (T) spiriva

Delivery Method

Duration

handi-haler, DPI; Respimat, SMI

twenty-four hrs

(G) aclidinium Bromide

trade brand?

Tudoroza

(G) aclidinium Bromide (T) Tudoroza

Type medication

Signal

LAMA very long acting muscarinic antagonist

maintenance drug for COPD

(G) Aclidinium Bromide (T) Tudoroza

Delivery method

Duration

Pressair, DPI inhaler

doze hr

(G) Glycopyrronium Bromide

Trade Brand

Seebri

(G) Glycopyrronium Bromide (T) Seebri

type medicine

indication

LAMA lengthy acting muscarinic antagonist

maintenance medicine for COPD

(G) Glycoppyrronium Bromide (T) Seebri

delivery method

duration

Breezhaler, DPI a lot like neohaler

12 human resources

(G) umeclidinium

trade term

Incruse

(G) umeclidinium (T) incruse

type drug

indications

MUSGO Long performing muscarinic antagonist

protection drug intended for COPD

(G) umeclidinium (T) incruse

Delivery Method

Duration

Ellipta, DPI

24 hr

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